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Top 13 San Francisco Healthcare Startups

Maksym Babych

Maksym Babych


11 min

San Francisco is synonymous with trailblazing startups.

As the epicenter of Silicon Valley, the city has birthed today’s tech giants like Google, Facebook, Apple, and more.

This entrepreneurial, innovative spirit also permeates San Francisco’s rapidly growing healthcare industry.

This article highlights 13 of San Francisco’s most promising healthcare startups to watch in 2024.

From reimagining primary care to decoding DNA and enabling at-home diagnosis, explore this curated list of trailblazers across the healthcare landscape.

Let’s dive in!

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Top San Francisco Healthcare Startups to Watch in 2024

We have curated a list of the best healthcare companies in SF.

These companies in San Francisco are setting new trends in healthcare.

1. HealerPlus

DescriptionHealerPlus is an app for medical practitioners to help them manage their business.

The app can automate everything from fees collection, communication, and everything else on the business side.

Market Positioning, Key Features & Key CustomersHealerPlus is a digital accountant for medical professionals.

Communications, filing the cases, client support, and billing – it automates all the activities.

It is a productivity tool for medical professionals.

The Key Customers for this startup are the medical practitioners that have to deal with clients directly.

FundingHealerPlus has not received funding from any VC yet.

It operates on the pre-seed investment of $1,000 from its founders.

Top 13 San Francisco Healthcare Startups


DescriptionElanza wellness is a healthcare startup that wishes to improve the mental well-being of people.

Ultimately helping them to conceive kids.

Elanza Wellness believes that the most prominent reason couples fail to conceive naturally is the stress/depression to do itself.

Market Positioning, Key Features & Key CustomersElanza wellness strives to position itself as a startup that helps people get out of depression and live their life happily.

It provides consultation through text messages that help customers relieve stress and focus on what’s important.

They believe that tension and depression further decrease the chances of natural conception in couples.

Their key customers are couples that are looking to have kids naturally. 

FundingElanza Wellness launched in 2021 with Pre-seed funding of $120,000 from Techstars New York City Accelerator.
Top 13 San Francisco Healthcare Startups

3. Heyday 

DescriptionHeyday claims to be the first interactive gym equipment provider for people over 55.

They provide a home gym device that has a screen built-in. And, it has courses and training from approved trainers.

You can learn more about their products and services by visiting their website. 

Market Positioning, Key Features & Key CustomersHeyday positions itself as a forward-looking startup that aims to improve the health and wellness of older people.

They are initially providing home gym equipment.

But, they may pivot to becoming a platform-based startup as well.

Their Key Customer market is narrow and targeted.

It comprises people aged above 55 who are interested in maintaining and improving their fitness. 

FundingHeyday launched in July 2021, and its funding has not been disclosed yet.

It might be keeping it private for legal reasons.

Since it is a gym equipment company, it can not operate without funding.

It is just that they do not want to disclose it at the moment.

Top 13 San Francisco Healthcare Startups

4. One Medical Group

Coming from a larger organization, the One Medical health startups San Francisco set up shop in 2018.

Among the premier healthcare startups, One Medical gives wellness & care services in San Francisco.

As one of the premier healthcare startups, One Medical offers services at the user’s convenience in San Francisco.

DescriptionThe main motive of these healthcare companies in San Francisco is to help you get easy access to a doctor.

For that, they provide a platform to have video consultations.

Further, One Medical staff testing, helping sanitize the office environment, and ensure compliances.

Working on a unique model than other health tech companies, these guys are making working in San Francisco safer.

Market Positioning, Key Features & Key CustomersComing from a telemedicine apps market, the value of such products will reach $64 Billion by 2025.

In cities like SF, the residents need on-demand and prompt wellness services.

Such healthcare trends are useful in driving the market.

The principal customers of such healthcare startups SF include;

  • Working Parents
  • Professionals
  • Younger students
  • Senior residents who have access to smartphones
  • Business owners
FundingCompared to other health tech companies, One Medical grabbed $350 Million in funding in San Francisco.

In total, $532 Million worth of funding is already capitalizing at One Medical.

Also, this has been the biggest sum of investment acquired by the group in its entire journey.

Top 13 San Francisco Healthcare Startups

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5. Allogene Therapeutics

There is a global race to find a cure for cancer.

Healthcare startups Allogene Therapeutics is working to make antigens out of San Francisco.

The purpose of the antigen is to enhance the immunological response to cancer.

Few health startups SF are working to build such solutions.

Allogene health tech is one of the few companies based in San Francisco working to find a cure.

DescriptionIn 2017, the National Cancer Institute spent $563 Million on Cancer cure research.

Cancer, as a disease, might have got some preventive techniques.

But various healthcare companies in SF and across the globe want to find a cure.

Allogene is also in the race to get a breakthrough.

Allogene is one of those health tech companies in San Francisco, which is trying to find a cure.

Market Positioning,

Key Features, &

Key Customers

The cancer research market cap is going to reach $180,193 Million by 2026.

Allogene is working on solutions to find a cancer cure.

Their feature product, AlloCAR T Therapy, is about building the next level therapy for cancer.

FundingIn a total of two funding rounds, Allogene has bagged around $531.8 Million.
Top 13 San Francisco Healthcare Startups

6. Hims & Hers

Hims and Hers is one of the unique healthcare startups San Francisco. They are working in telemedicine and patient engagement.

Such health tech companies’ San Francisco aims to create an impact.

They tend to create modern telemedicine solutions and effective products.

Startups like Him and Hers makes it easier to access health and wellness services in San Francisco.

DescriptionHims and Hers is providing help with digital solutions.

Along with this, it is also an eCommerce platform for selling products.

Following suit with other health tech companies SF, they deal with telemedicine.

Hims and Hers is on a mission to allow the users to get access to easy healthcare.

Various similar startups in San Francisco are also allowing people to consult doctors for health care.

Market Positioning,

Key Features, &

Key Customers

As per a report, the global video consultation market will grow at 7.6% between 2019 to 2026.

Around 70% of the users in the US prefer consulting via video calls.

Seeing this, almost every patient is a potential customer for the health tech companies San Francisco.

FundingHims and Hers got $100 Million funding in 2019.

It is Unicorn health startups, San Francisco, with a valuation of $1 Billion.

In total, this health startup in San Francisco has raised around $197 Million in funding.

Top 13 San Francisco Healthcare Startups

7. Orphidia

Medical testing is gaining ground in the wellness and patient care industry.

Health startups San Francisco like Orphidia, are working to streamline medical testing.

Also, they are making it easier to gather and understand patient data.

DescriptionCorrect diagnosis means that the patients can get proper treatment.

Thus, such companies in San Francisco provide cloud-based healthcare tests.

The USP is that as the tests are conducted, the results are faster, accurate, and stored in a repository.

Also, Orphidia is a part of the growing health startups SF.

They also ensure the adequate security of the data.

Market Positioning,

Key Features &

Key Customers

Healthcare companies working on direct-to-customer labs in San Francisco are growing.

The exact numbers to pinpoint the growth is not present with clarity.

Due to the benefits that come from such solutions, almost every patient is a potential customer.

FundingAs of yet, Orphidia is at the seed funding stage.

Due to this, the exact data about the funding amount is not available.

Top 13 San Francisco Healthcare Startups

8. Lively

Lively is a modern-day Health and Savings account manager startups in San Francisco.

Such startups help residents of San Francisco make smart decisions about their healthcare needs.

Lively is one of the few healthcare startups San Francisco working on this model.

DescriptionAs a new age and unique healthcare companies in San Francisco, Lively is a care management organization.

Care management firms go beyond standard wellness services and develop solutions for other tasks.

Market Positioning, Key Features, &

Key Customers

Lively is rated as the top health startups San Francisco working on this model.

Also, the cumulative care management industry is expected to reach $37.94 Billion by 2027.

At present, such health tech companies are only at a nascent stage in San Francisco.

Couple this with the fact that almost every patient needs effective management solutions.

Hence, building one of your health startups, San Francisco, on this model, will be profitable.

FundingIn the latest series B funding round for health companies in San Francisco, Lively got $27 Million.

This brings the total funding amount to $42 Million in just 4 years of its establishment.

Top 13 San Francisco Healthcare Startups

9. Alto

Another one of the care management solutions based health tech companies SF.

Alto is a smart solution provider for patient prescriptions.

Along with ensuring timely delivery, they also provide recommendations (which is a unique feature).

DescriptionSeveral healthcare companies in San Francisco are developing solutions to decrease wellness costs.

Health startups like Alto take the lead with helping San Francisco residents save costs on the prescriptions.

They have a cloud-based repository where the doctors and patients can upload the prescriptions.

Alto will automatically find the lowest rate of medicines for the customer and also deliver them.

Such healthcare solutions are a buzz with startups founders because of the big market in San Francisco.

Market Positioning, Key Feature, & Key CustomersThe ePharmacy business model is also very profitable in the future.

In 2018, the market value of such healthcare companies in the world, and not only San Francisco, was $50,000 million.

However, the estimated growth of 17.3 % CAGR puts the total value at $180,000 approx.

Healthcare companies working on this model have a huge scope in San Francisco and any other market.

Further, they embed features like chat, price comparison, and delivery.

Such healthcare companies in San Francisco have great potential.

FundingIn the latest Series D Round Alto Pharmacy bagged $250 Million.

Adding this to the total tally, they have got $356 Million in funding since introduction.

Top 13 San Francisco Healthcare Startups

10. Hinge Health

Patient-centric solutions are gaining importance. Thus, healthcare startups SF, like Hinge Health, is developing new solutions.

Such tech companies help San Francisco patients with specific health issues.

Similarly, Hinge health helps with back pain and chronic pain issues.

This is done digitally via their application and doctors-backed recommendations.

DescriptionHinge Health is one of the innovative startups helping professionals in San Francisco cure back pain.

They solely focus on joint pains and back pain, in turn, improving overall body physique.

Market Positioning,

Key Features, & Key Customers

Every 4 in 5 employers dealing with musculoskeletal issues use the solutions provided by Hinge Health.

This means that they have a big market presence.

Not many health tech companies San Francisco target a specific issue of the users.

This company provides solutions to MSK with the help of professional doctors and coaches.

They provide therapy, support, and education for the condition.

FundingIn the latest Series C round of funding, the company raised $90 Million.

Further, crossing various other healthcare startups, San Francisco, Hinge health has got $126.1 Million in 5 funding rounds.

Top 13 San Francisco Healthcare Startups

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11. Clarify Health

Clarify is working in the healthcare domain and other startups in San Francisco to deliver precise and detailed insights.

Healthcare companies like Clarify work in collaboration with San Francisco wellness professionals.

From physicians to ACOs, they create some real impact.

DescriptionHealth startups resembling Clarify are working in San Francisco to streamline the behind the curtain functions.

This means that provide recommendations that help users observe a fall in:

  • Medical Cost
  • Referrals

Further, they have helped increase:

  • Savings
  • Disease Identification
Market Position, Key Customers, & Key FeaturesClarify leverages from big data to deliver solutions.

The market value of using big data in wellness will reach $68.82 Billion by 2025.

The customer base of Clarify consists of both patients and physicians.

Patients receive help with care provisioning and risk identification.

Physicians can also benefit from these types of health startups San Francisco.

They can get help with:

  • Personalizing care
  • Effective therapy
FundingIn a total of 2 funding rounds, Clarify has got $63 Million.
Top 13 San Francisco Healthcare Startups

12. Tonal

Tonal is working in the domain of intelligent fitness systems that can be installed in homes.

Such health tech companies San Francisco have a high scope of growth in the time of a pandemic.

DescriptionHome gyms are gaining popularity with every passing day.

People are more comfortable working from home rather than going out.

Due to this, healthcare startups in San Francisco can build such solutions.

However, this can also be due to the lack of time and accessibility to a good gym.

Thus, startups like Tonal are providing the residents of San Francisco with innovative health solutions.

Not only SF, but Tonal has a wide market presence.

Market Positioning, Key Features, & Key CustomersThe smart healthcare industry is valued at $143.6 Billion.

Tonal and many other similar companies in San Francisco are providing modern healthcare solutions.

Tonal also provides the required equipment that is fitted with a digital weight system.

Combined with next-gen hardware, such systems heavily rely on better technology.

FundingWith a total of 4 funding rounds for health tech companies, San Francisco, Tonal has raised $90 Million.
Top 13 San Francisco Healthcare Startups

13. Verily

Health tech companies San Francisco like Verily, boast an evidence-based care system.

Such tech companies allow San Francisco residents to choose the best health services.

As one of the innovative startups in San Francisco, Verily allows the physicians to give personalized health services.

DescriptionEffective healthcare depends on accurate information.

Healthcare startups San Francisco provides data analytical solutions.

With better information, patients can make better wellness decisions.

On the other hand, physicians can also benefit from health tech companies SF working on such work models.

Market Positioning, Key Features, & Key CustomersPatient-centric market valuation was $10,235 Million in 2016.

However, by 2023, this valuation will reach $113,728 Million.

Verily works to provide screening, securitizing the data, and help respond to emergencies.

Healthcare companies in SF that provide patient-centric services take care of a few things.

  • Customer needs
  • Physician needs
  • Existing care ecosystems
  • The interdependence of the entire system

The recommendations are subject to these results, which further helps make decisions.

FundingSan Francisco based Verily has got one of the biggest funding among healthcare companies in the city.

In 2019, Verily got $1 Billion in funding as private equity.

This brings the cumulative funding of the company to $1.8 Billion.

Ready to Launch Your Own Healthcare Startup?

The healthcare industry in San Francisco continues to grow and innovate at a rapid pace.

However, launching a successful healthcare startup is no easy feat. It requires thorough market validation, strategic business planning, and seamless execution.

That’s where working with an experienced development firm can make all the difference.

Our team has in-depth expertise in designing, developing, and delivering healthcare technology solutions.

We provide end-to-end services – from market analysis and MVP creation to UI/UX design, software engineering, DevOps, project management, and more.

Our thoughtful approach helps founders refine their vision, accelerate time-to-market, and stand out from the competition.

Schedule a free consultation to discuss your goals and how SpdLoad can help bring your healthcare startup vision to life. Reach out today to get started!

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